Mfg Part Number
Ab03472-1.1
Vector Labs Ab03472-1.1 Anti-Aspartate beta-hydroxylase [G3-F11], Mouse IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing mice with naked plasmid DNA containing N-terminal domain of encoding HAAH gene and recombinant HAAH polypeptide.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | G3-F11 |
| Synonyms: | HAAH; ASPH; BAH; ASP beta-hydroxylase; Aspartyl beta-hydroxylase; Aspartyl/asparaginyl beta-hydroxylase; Peptide-aspartate beta-dioxygenase; G3/F11; G3; F11 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; WB; IHC |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 21466288 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody recognizes and binds human aspartyl/asparaginyl beta-hydroxylase. The human aspartyl (asparaginyl) beta-hydroxylase (HAAH) is an a-ketoglutarate-dependent dioxygenase, which is a membrane-associated and highly conserved enzyme that hydroxylates epidermal growth factor-like domains in transformation-associated proteins. Overexpression of HAAH is recognized as an indicator for carcinomas in humans. |
| Application Notes: | The specificity and sensitivity of this antibody for human aspartyl (asparaginyl) beta-hydroxylase (HAAH) was determined using ELISA and western blot (PMID: 19663697). This antibody was also used in the identification of HAAH expression in seven tumor tissues, including hepatocellular carcinoma, lung cancer, kidney cancer, cholangiocarcinoma, prostate cancer, breast cancer, and glioblastoma by immunohistochemical stain (PMID: 19663697; 25394783). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |