Mfg Part Number
Ab03501-10.3
Vector Labs Ab03501-10.3 Anti-Sortilin-related receptor [93201], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
Vector Labs Ab03501-10.3 Anti-Sortilin-related receptor [93201], Human IgG1, Fc Silent™, kappa (100 μg)
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 93201 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | SORL1; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LDLR relative with 11 ligand-binding repeats; LR11; SorLA-1; Sorting protein-related receptor containing LDLR class A repeats; SorLA |
| Amount: | 100 μg |
| Application Codes Clone: | X-ray crystallography |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody binds the Vps10p domain of the human sortilin-related receptor. Sortilin-related receptor 1 (SORL1) encodes a large, multi-domain containing, membrane-bound receptor involved in endosomal sorting of proteins between the trans-Golgi network, endosomes and the plasma membrane. The sorting of proteins is essential for normal cell function and defects in these pathways are thought to be important factors in the pathogenesis of Alzheimer’s disease (AD). |
| Application Notes: | This antibody can be used for the identification of sortilin-related receptor. A fragmented version of this antibody was used in crystallizing a protein (US10513562). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |