Mfg Part Number
Ab03508-1.1
Vector Labs Ab03508-1.1 Anti-LAG-3 [209B1], Mouse IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing female BALB/c mice with Flag-his-tagged extracellular domain of LAG-3.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 209B1 |
| Synonyms: | CD223; LAG3; FDC; Lymphocyte activation gene 3 protein |
| Amount: | 100 μg |
| Application Codes Clone: | SPR; inhibition |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG4 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG4 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | The antibody is specific for human LAG-3. |
| Application Notes: | The antibody is a humanized version of the mouse antibody MAB209B1. The binding affinity of the antibody to hLAG-3 was measured by surface plasmon resonance. The binding affinity of this antibody towards human LAG-3 was found to be Kd= 7.7pM. The antibody showed a good tumour inhibitory effect in in vivo application (WO2021136392). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |