Mfg Part Number
Ab03513-1.159-BS
Vector Labs Ab03513-1.159-BS Anti-non-structural protein 4 [Nb41], Mouse IgG1-Fc Fusion, (1 mg)
Quick Overview
An adult male bactrian camel was immunized subcutaneously with the purified Nsp4-NHis recombinant protein. A camel VHH library was then constructed and panned against Nsp4.
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| Product Class: | Purified |
|---|---|
| Clone ID: | Nb41 |
| Synonyms: | NSP4; Replicase polyprotein 1ab; ORF1ab polyprotein |
| Amount: | 1 mg |
| Application Codes Clone: | ELISA; in vitro |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS only. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | The antibody is specific for Nsp4. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by indirect ELISA analysis. MARC-145 cell lines expressing nanobodies were generated and infected with PRRSV strain SD16. At 24 h post-infection the antibody inhibited infectious virus release by about 99%. Further, the antibody protected MARC-145 cells from any virus-induced cytopathic effect and fully blocked PRRSV replication (Liu et al. 2016; PMID: 27010387). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |