Mfg Part Number
Ab03518-1.159-BS
Vector Labs Ab03518-1.159-BS Anti-Nsp9 [Nb6], Mouse IgG1-Fc Fusion, (1 mg)
Quick Overview
A Bactrian camel was immunized with recombinant Nsp9 protein and a VHH library was constructed. The antibody was isolated by panning against Nsp9.
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| Product Class: | Purified |
|---|---|
| Clone ID: | Nb6 |
| Synonyms: | nonstructural protein 9; PRRSV; Replicase polyprotein 1ab; ORF1ab polyprotein |
| Amount: | 1 mg |
| Application Codes Clone: | inhibition |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS only. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | The antibody is specific for Nsp9 of PRRSV (strains SD-16, JXA1, GD-HD, and VR2332). Nsp9 possesses RNA-dependent RNA polymerase (RdRp) activity that is essential for genome replication and transcription. |
| Application Notes: | MARC-145 cell lines stably expressing Nb6 were established and infected with PRRSV strain SD-16. Virus infection was strongly suppressed in MARC-145-Nb6 as shown by IFA. Further, the antibody could inhibit PRRSV replication (Liu et al., 2015; PMID: 26525739). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |