Mfg Part Number
Ab03525-23.0
Vector Labs Ab03525-23.0 Anti-gp41 [A7], Rabbit IgG, lambda (100 μg)
Quick Overview
A phage immune library generated from a long-term non-progressors with HIV neutralizing antibodies in his plasma. The phage library was screened on recombinant soluble gp140 envelope (Env) proteins and the antibody was isolated.
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| Product Class: | Purified |
|---|---|
| Clone ID: | A7 |
| Synonyms: | Envelope glycoprotein GP41; transmembrane protein gp41 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; in vitro neutralization |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length chimeric rabbit antibody was made using the variable domain sequences of the original Human scFv format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | The antibody is specific for gp41, and it binds to structural elements of the third variable loop V3. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody showed neutralizing activity against a panel of standardized Tier 1 and Tier 2 HIV-1 pseudo virions on Tzm-bl cells (Trott et al., 2014; PMID:24828352). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |