Mfg Part Number
Ab03546-2.3
Vector Labs Ab03546-2.3 Anti-3–5 ring polycyclic aromatic hydrocarbons (PAHs) [2G8], Mouse IgG2a, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing Balb/c mice were with 1-pyrene butyric acid-KLH.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 2G8 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | unsubstituted PAH; 2-methylphenanthrene; 9,10-dimethylanthracene; 7,12 dimethybenz(a)anthracene; 4-methyl dibenzothiophene; Benzo(a)pyrene; Chrysene; Pyrene; Phenanthrene; Anthracene |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | The antibody shows general selectivity and high sensitivity to a variety of 3–5 ring PAH, but it shows a low affinity for 2-ring PAHs. Polycyclic aromatic hydrocarbons (PAHs), a group of organic compounds composed of two or more blended aromatic rings, are an important class of environmental pollutants |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody could inhibit unsubstituted and methylated PAHs by indirect competitive ELISA. IC50 values for unsubstituted PAHs ranged from 1.68 μg/L to 9.44 μg/L, while IC50 values against methylated PAHs (2-methylphenanthrene, 9,10-dimethylanthracene, 7,12 dimethybenz(a)anthracene, 4-methyl dibenzothiophene) were ranging from 1.92 μg/L to 31 μg/L. The antibody was employed in the KinExA Inline Biosensor system for quantifying 3–5 ring PAHs in aqueous environmental samples (detection limit 0.2 μg/L) (Li et al., 2016; PMID: 26925369). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |