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Mfg Part Number

Ab03579-1.29-BS

Vector Labs Ab03579-1.29-BS Anti-Bordetella pertussis cells [scFv 18], Mouse Fab fragment, His-Tagged, kappa (1 mg)

VECTOR LABS

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Quick Overview

This antibody was generated by immunizing a BALB/c mouse with 0.1 ml of the commercial pertussis vaccine Quandracel. From this DNA a phage display library was created and panned against B. pertussis whole cells so find this clone.

$5,162.30

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Description

Product Class: Purified
Clone ID: scFv 18
Heavy Chain Modification: His-Tagged
Synonyms: filamentous hemagglutinin; FHA; pertactin; PRN; pertactin autotransporter; P.93; Pertactin; Filamentous hemagglutinin transporter protein FhaC; TpsB transporter; fhaC
Amount: 1 mg
Application Codes Clone: ELISA; functional assay
Shipping Temperature: Wet Ice
Buffer Composition: PBS only.
Original Format: scFv
Storage Temperature: Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody is specific for pertactin and filamentous hemagglutinin of Bordetella pertussis. Filamentous hemagglutinin is a member of a two partner secretion pathway (TPS) in which it mediates the secretion of filamentous hemagglutinin FHA (fhaB). Pertactin may have a role in bacterial adhesion, and thus play a role in virulence.
Application Notes: The scFv version of this antibody was used for an ELISA on filamentous hemagglutinin (FHA), pertactin (PRN) and B. pertussis cells. The antibody was positive very every antigen tested. The scFv version of this antibody was tested for its ability to inhibit B. pertussis binding to HEp-2 cells, it did not show any inhibition. (Hussein et al, 2007; pmid:17724067).

Product Class:	Purified
Clone ID:	scFv 18
Heavy Chain Modification:	His-Tagged
Synonyms:	filamentous hemagglutinin; FHA; pertactin; PRN; pertactin autotransporter; P.93; Pertactin; Filamentous hemagglutinin transporter protein FhaC; TpsB transporter; fhaC
Amount:	1 mg
Application Codes Clone:	ELISA; functional assay
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS only.
Original Format:	scFv
Storage Temperature:	Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody is specific for pertactin and filamentous hemagglutinin of Bordetella pertussis. Filamentous hemagglutinin is a member of a two partner secretion pathway (TPS) in which it mediates the secretion of filamentous hemagglutinin FHA (fhaB). Pertactin may have a role in bacterial adhesion, and thus play a role in virulence.
Application Notes:	The scFv version of this antibody was used for an ELISA on filamentous hemagglutinin (FHA), pertactin (PRN) and B. pertussis cells. The antibody was positive very every antigen tested. The scFv version of this antibody was tested for its ability to inhibit B. pertussis binding to HEp-2 cells, it did not show any inhibition. (Hussein et al, 2007; pmid:17724067).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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