Mfg Part Number
Ab03594-1.29-BS
Vector Labs Ab03594-1.29-BS Anti-LAM [BJRbL03], Mouse Fab fragment, His-Tagged, kappa (1 mg)
Quick Overview
This antibody was generated by immunizing a rabbit with Mycobacterium tuberculosis H37Rv cell wall.
$5,162.30
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| Product Class: | Purified |
|---|---|
| Clone ID: | BJRbL03 |
| Heavy Chain Modification: | His-Tagged |
| Synonyms: | Lipoarabinomannan; Mycobacterium cell wall polysaccharide |
| Amount: | 1 mg |
| Application Codes Clone: | ELISA; FC; functional assay |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS only. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Rabbit IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the LAM protein of Mycobacterium tuberculosis but shows cross-reactivity with other Mycobacterium species like M. bovis. M. tuberculosis causes the disease tuberculosis. |
| Application Notes: | The ability of the rabbit version of this antibody to bind LAM was determined using ELISA on LAM. Furthermore, the affinity of this antibody to LAM was determined using a ForteBio Octe machine. Finally, the ability of this antibody to distinguish isolates of M. tuberculosis (MTB), M. avium-intracellulare (MAI), M. abscessus, and M. fortuitum-abscessus (MA-MF) was assessed using flow cytometry; it bound all bacteria (Yan et al., 2021; PMID: 32146163). This antibody was used as a capture antibody in a sandwich ELISA (Yan et al., 2023; PMID: 37764103). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |