Mfg Part Number
Ab03609-3.3
Vector Labs Ab03609-3.3 Anti-VLP of CPV-VP2 [scFv 96], Mouse IgG2b, Fc Silent™, lambda (100 μg)
Quick Overview
This antibody was raised by first immunizing twelve-week old white Leghorn hens intramuscularly with CPV-VLP. A library was then constructed from these chickens and panned against CPV-VLP.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | scFv 96 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Coat protein VP2 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; neutralization |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length, chimeric mouse antibody was made using the variable domain sequences of the original Chicken scFv format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the VP2 for the Canine Parvovirus. VP2 is a capsid protein that self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The Canine Parvovirus is a disease mainly affecting dogs with a 91% mortality rate. |
| Application Notes: | To analyse the sensitivity of the scFv version of this antibody an ELISA was performed on CPV-VP2. Furthermore, the ability of this antibody to prevent a CPV infection was determined, it showed a decrease of 30% over 72 hours (Ge et al, 2020; pmid:32883344). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |