Mfg Part Number
Ab03621-1.159-BS
Vector Labs Ab03621-1.159-BS Anti-Lysozyme [cAbHul6], Mouse IgG1-Fc Fusion, (1 mg)
Quick Overview
Phage libraries were generated using the mRNA extracted from the lymphocytes of immunized dromedaries. The VHH antibody was isolated by biopanning from the libraries.
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| Product Class: | Purified |
|---|---|
| Clone ID: | cAbHul6 |
| Synonyms: | 1,4-beta-N-acetylmuramidase C; cAb-Hul6; NbHuL6 |
| Amount: | 1 mg |
| Application Codes Clone: | SPR; Crystallization |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS only. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | The antibody is specificity for human lysozyme. It does not cross react with hen lysozyme. |
| Application Notes: | The binding affinity of the VHH fragment for human lysozyme was measured by surface plasmon resonance (Kd = 0.7 nM) (Dumoulin et al., 2002; PMID: 11847273). The antibody stabilized an unstable human lysozyme mutant that forms fibrils and amyloids.The crystal structure of the original version of the antibody in complex with human lysozyme was determined (Dumoulin et al., 2003; PMID: 12917687). The original antibody was humanized and the binding affinity for human lysozyme was measured by surface plasmon resonance (Kd = 2.36 nM). The crystal structure of the humanized version of the antibody in complex with human lysozyme was determined (Vincke et al., 2009; PMID: 19010777). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |