Mfg Part Number
Ab03633-23.0
Vector Labs Ab03633-23.0 Anti-gp41 [SL5], Rabbit IgG, lambda (100 μg)
Quick Overview
A single chain fragment variable (scFv) phage display library was constructed from a simian immunodeficiency virus (SIV)-infected rhesus macaque. The original antibody was isolated by panning onto oligomeric (gp140) and monomeric (gp120) forms of SIV Env glycoprotein.
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| Product Class: | Purified |
|---|---|
| Clone ID: | SL5 |
| Synonyms: | Envelope glycoprotein gp160; Transmembrane protein gp41; Glycoprotein 41 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; neutralization |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length chimeric rabbit antibody was made using the variable domain sequences of the original scFv format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | The antibody is specific for gp41. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis. The scFv format was able to neutralize SIVmac316. The original antibody was converted in the scFv-Fc format and its specificity validated by WB (Ita et al., 2017; PMID: 28075174). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |