Mfg Part Number
Ab03636-10.3
Vector Labs Ab03636-10.3 Anti-NS1 [clone n.11], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was originated from a phage display library by panning against the NS1 protein.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | clone n.11 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Non-structural protein-1; NS1A |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; WB; inhibition |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length reformatted human antibody was made using the variable domain sequences of the original Human scFv format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | The antibody is specific for the E domain of the non-structural protein-1. The antibody reacts with viruses belonging to different subtypes and types including avian H5N1, swine H1N1 and H3N2, human H1N1 and H3N2 and influenza B virus. Non-structural protein-1 (NS1) is a multifunctional and conserved protein of influenza viruses. It is produced at the initial phase of the infection for suppressing and evading the host immune responses and enhancing the viral replication. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody detected the E domain of NS1 by western blot analysis. The clone could enter the influenza virus infected cells and interfered with the NS1 activities leading to replication inhibition of viruses belonging to different subtypes and types including avian H5N1, swine H1N1 and H3N2, human H1N1 and H3N2 and influenza B virus (Yodsheewan et al. 2013; PMID: 23928258). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |