Vector Labs Ab03675-10.0 Anti-Junin virus GP1 [OD01], Human IgG1, kappa (100 μg) Centrifuge Bundle Savings at Sycamore Life Sciences

Description

Product Class: Purified
Clone ID: OD01
Synonyms: JUNV GP1; GPC; Glycoprotein G1; Pre-glycoprotein polyprotein GP complex; Argentinian mammarenavirus; Pre-GP-C; eOD01; OD01-AA09; J202; nAb OD01
Amount: 100 μg
Application Codes Clone: ELISA; WB; IP; IF; neutralize
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody binds an epitope in the hTfR1 binding site of the GP1 subunit of envelope glycoprotein of Junin virus (JUNV). Junin virus also known as Argentinian mammarenavirus is an arenavirus in the Mammarenavirus genus which causes Argentine Haemorrhagic Fever (AHF). Mammarenaviruses sporadically cause zoonotic infections in humans, which may lead to life-threatening viral haemorrhagic fever (VHF) disease. VHFs caused by arenaviruses are acute diseases with considerable mortality rates. Symptoms are fever, malaise, headache, nausea, diarrhea, petechial hemorrhage of the soft tissues, lethargy, and irritability. Members of the Arenaviridae family are enveloped viruses with a bi-partite RNA genome coding for four viral proteins. The virus is spread through the aerosolization of host rodent excreta.
Application Notes: This antibody can bind GP1 of Junin virus (XJ45 strain) in an ELISA. This antibody was used for the indirect immunofluorescent staining of Junin virus infected Vero cells. This antibody shows weak reaction with Junin GP1 in immunoprecipitation and western blot. This antibody can also neutralize Junin virus in an in vitro assay (PMID: 2471803). This antibody shows mild neutralization of Candid #1 strain in a plaque neutralization assay (PMID: 27044104).

Product Class:	Purified
Clone ID:	OD01
Synonyms:	JUNV GP1; GPC; Glycoprotein G1; Pre-glycoprotein polyprotein GP complex; Argentinian mammarenavirus; Pre-GP-C; eOD01; OD01-AA09; J202; nAb OD01
Amount:	100 μg
Application Codes Clone:	ELISA; WB; IP; IF; neutralize
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody binds an epitope in the hTfR1 binding site of the GP1 subunit of envelope glycoprotein of Junin virus (JUNV). Junin virus also known as Argentinian mammarenavirus is an arenavirus in the Mammarenavirus genus which causes Argentine Haemorrhagic Fever (AHF). Mammarenaviruses sporadically cause zoonotic infections in humans, which may lead to life-threatening viral haemorrhagic fever (VHF) disease. VHFs caused by arenaviruses are acute diseases with considerable mortality rates. Symptoms are fever, malaise, headache, nausea, diarrhea, petechial hemorrhage of the soft tissues, lethargy, and irritability. Members of the Arenaviridae family are enveloped viruses with a bi-partite RNA genome coding for four viral proteins. The virus is spread through the aerosolization of host rodent excreta.
Application Notes:	This antibody can bind GP1 of Junin virus (XJ45 strain) in an ELISA. This antibody was used for the indirect immunofluorescent staining of Junin virus infected Vero cells. This antibody shows weak reaction with Junin GP1 in immunoprecipitation and western blot. This antibody can also neutralize Junin virus in an in vitro assay (PMID: 2471803). This antibody shows mild neutralization of Candid #1 strain in a plaque neutralization assay (PMID: 27044104).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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