Mfg Part Number
Ab03684-10.3
Vector Labs Ab03684-10.3 Anti-NADPH oxidase 2 [NL7], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The antibody was generated by immunizing BALB/c mice with Cyt b.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | NL7 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | NOX2; CYBB; flavocytochrome b; Cyt b; Cytochrome b-245 heavy chain; CGD91-phox; Cytochrome b(558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; gp91-1; gp91-phox; gp91phox; p22 phagocyte B-cytochrome |
| Amount: | 100 μg |
| Application Codes Clone: | WB; FC; inhibition |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 16563510 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody recognises NADPH oxidase 2 (Epitope EKDVITGLK). The antibody cross-reacts with PDIA3. |
| Application Notes: | The antibody detected gp91phox by western blot analysis (Burritt et al., 2003; PMID: 12794137 and Bechor et al., 2015; PMID: 25699251). This antibody was used for detection of gp91phox by flow cytometry. The specificity of the antibody for gp91phox was further confirmed by phage display epitope mapping. The antibody inhibited the NADPH oxidase activity before or during the initial stages of electron transfer (Burritt et al., 2003; PMID: 12794137). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |