Mfg Part Number
Ab03685-10.3
Vector Labs Ab03685-10.3 Anti-Cytochrome b-245 light chain [NS5], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
Vector Labs Ab03685-10.3 Anti-Cytochrome b-245 light chain [NS5], Human IgG1, Fc Silent™, kappa (100 μg)
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | NS5 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | CYBA; flavocytochrome b; Cyt b; Cytochrome b(558) alpha chain; Cytochrome b558 subunit alpha; Neutrophil cytochrome b 22 kDa polypeptide; Superoxide-generating NADPH oxidase light chain subunit; p22 phagocyte B-cytochrome; p22-phox; p22phox |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; WB; IP |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 16563510 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody recognises Cytochrome b-245 light chain (Epitope LLEYPRG+VKLFGP). |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody detected p22phox by western blot analysis. Further, the antibody immunoprecipitated Cyt b. The antibody showed moderate levels of inhibition of superoxide production by the NADPH oxidase complex (Taylor et al., 2004; PMID: 15585859). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |