Mfg Part Number
Ab03693-23.0
Vector Labs Ab03693-23.0 Anti-Herpes simplex virus [H37], Rabbit IgG, kappa (100 μg)
Quick Overview
The Fab fragment was selected from a human combinatorial antibody library constructed in a phage-display vector by a panning procedure against an HSV lysate.
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| Product Class: | Purified |
|---|---|
| Clone ID: | H37 |
| Synonyms: | HSV |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; IF |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | Fab |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody binds to herpes simplex virus (HSV) antigens. The antibody is reactive with HSV-1 and HSV-2. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis. The Fab was able to specifically recognize Vero cells infected with HSV in indirect immunofluorescence (IF) assays; in particular, it recognized cells infected by either HSV type 1 (HSV-1) or HSV-2. This Fab was tested in indirect IF assays against Vero cells infected with two reference HSV strains and against Vero and HEp-2 cells infected by 72 HSV-1 and 62 HSV-2 clinical isolates. The Fab gave a strong positive fluorescent signal with the F (HSV-1) and G (HSV-2) reference strains and with all the HSV-1 and HSV-2 clinical isolates tested. The detection sensitivity with the Fab in indirect IF assays was higher overall than that provided by the type-specific murine monoclonal antibodies (Cattani et al., 1997; PMID:9163470). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |