Mfg Part Number
Ab03714-10.0
Vector Labs Ab03714-10.0 Anti-IL-4 [12-6-68], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice subcutaneously with 25 µg of human IL-4 in 100 µl of 150 mM sodium chloride emulsified with 100 µl of complete Freund’s adjuvant.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 12-6-68 |
| Synonyms: | IL4; BSF-1; Interleukin-4; B-cell stimulatory factor 1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds human IL-4. Interleukin-4 is a cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. It induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. It also induces expression of class II MHC molecules on resting B-cells and enhances both secretion and cell surface expression of IgE and IgG1. |
| Application Notes: | The binding of this antibody to human IL-4 was confirmed with ELISA (PMID: 12825686). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |