Mfg Part Number
Ab03725-3.0
Vector Labs Ab03725-3.0 Anti-Siglec-7 [Siglec7-01], Mouse IgG2b, lambda (100 μg)
Quick Overview
The original antibody was isolated from a human Fab antibody library by panning against human siglec-7.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | Siglec7-01 |
| Synonyms: | CD328; SIGLEC7; AIRM1; AIRM-1; SIGL7; CDw328; D-siglec; p75; Sialic acid-binding Ig-like lectin 7; Adhesion inhibitory receptor molecule 1; QA79 membrane protein |
| Amount: | 100 μg |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds human siglec-7. It is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. |
| Application Notes: | This antibody can bind recombinant human siglec-7 protein in an ELISA and western blot. The binding affinity of the IgG antibody for human siglec-7 was reported to be Kd= 71.5 nM. In vitro, this antibody was capable of enhancing killing effect of NK cells on tumor cells (CN106831989). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |