Mfg Part Number
Ab03760-23.0
Vector Labs Ab03760-23.0 Anti-3K11 idiotype [AI-K11B], Rabbit IgG, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing mouse with anti-morphine antibody 3K11 conjugated with KLH.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | AI-K11B |
| Synonyms: | 3K11; anti-idiotypic monoclonal antibody 3K11; opioid receptor |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody specifically binds anti-morphine antibody 3K11. It is an idiotypic antibody which exhibits the antigenic properties of morphine, binds to opioid receptors. When used for immunization, it induces the production of antibodies that specifically recognize morphine derivatives like 6-hemisuccinyl (GSM), 3-O-carboxymethyl (KMM) and 2-p-carboxy-phenylazomethyl (FAM) esters. |
| Application Notes: | This antibody is capable of binding to opioid receptors on T98G human glioblastoma cells. This antibody could also recognize conjugate of mAb 3K11 - horseradish peroxidase with 6-hemisuccinyl morphine ester-BSA in an ELISA. The binding affinity of this idiotype antibody to 3K11 was determined to be Kd = 3.2 nM. When rabbits were immunized with AI-K11B antibody, they generated antibodies that were capable of recognizing all tested derivatives of morphine (RU2745374). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |