Mfg Part Number
Ab03764-1.1
Vector Labs Ab03764-1.1 Anti-CD20 [VET308 (CD20-5)], Mouse IgG1, lambda (100 μg)
Quick Overview
The original antibody was generated by immunizing mice with CHO-DG44 cells expressing canine CD20.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | VET308 (CD20-5) |
| Synonyms: | MS4A1; B-lymphocyte antigen CD20; Membrane-spanning 4-domains subfamily A member 1 |
| Amount: | 100 μg |
| Application Codes Clone: | FC; IHC; functional assay |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody binds canine (dog) CD20 and cross reacts with feline (cat) CD20. This protein plays an important role in the regulation of cellular calcium influx necessary for development, differentiation, and activation of B-lymphocytes. |
| Application Notes: | The binding reactivity of this antibody to recombinant dog and cat CD20 expressed on the surface of CHO cells was determined using flow cytometry. This antibody binds recombinant dog CD20 with a binding affinity of Kd= 1.2 nM. This antibody exhibited a strong staining of B cells in a immunohistochemical staining of lymph node tissues collected from dogs with B-cell lymphoma. The ability of this antibody to alter the proliferation of lymphoma cells was checked using cell assays. This antibody was reported to cause a 60% reduction in proliferation of lymphoma cells (US9616120). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |