Mfg Part Number
Ab03767-10.0
Vector Labs Ab03767-10.0 Anti-CA242 [WT 1-31], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated from its parental mouse antibody by introducing point mutations in CDRs to improve binding affinity.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | WT 1-31 |
| Synonyms: | CA 242; C242:II; Carbohydrate antigen 242; tumor marker; pancreatic cancer |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds CA242, which is a carbohydrate tumor marker, closely related, but not identical, to CA 19-9 and CA 50. It is commonly tested along with CEA, CA19-9 for detecting pancreatic cancer. This protein is overexpressed in malignant tumors and has been clinically used as a diagnostic biomarker for pancreatic, colorectal and other cancers. |
| Application Notes: | This antibody binds human CA242 with a binding affinity of Kd= 9.48 nM. This antibody can be used for the detection of human CA242 in a sample using ELISA (CN112898430). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |