Mfg Part Number
Ab03779-10.0
Vector Labs Ab03779-10.0 Anti-CD257 (BAFF) [ABL-1], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing mice with human BAFF protein.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | ABL-1 |
| Synonyms: | BLyS; TNFSF13B; TALL-1; TNFSF20; ZTNF4; Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; B-cell-activating factor; Dendritic cell-derived TNF-like molecule; TNF and APOL-related leukocyte expressed ligand 1 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length, chimeric human antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds human BAFF protein. B-cell-activating factor (BAFF/CD257) is a cytokine belonging to the tumour-necrosis factor (TNF) family. This cytokine binds to TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. BAFF is a survival factor for B cells that controls B-cell maturation. It is also involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. |
| Application Notes: | This antibody binds recombinant human BAFF (amino acids A134-L285) with a binding affinity of 0.9 X 10^(-8) M. This antibody does not cross react with APRIL protein. This antibody was also capable of detecting native and recombinant forms of human BAFF protein in a western blot assay (PMID: 16023370). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |