Vector Labs Ab03780-23.0 Anti-CD257 (BAFF) [NMB04], Rabbit IgG, kappa (100 μg) Centrifuge Bundle Savings at Sycamore Life Sciences

Description

Product Class: Purified
Clone ID: NMB04
Synonyms: BLyS; TNFSF13B; TALL-1; TNFSF20; ZTNF4; Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; B-cell-activating factor; Dendritic cell-derived TNF-like molecule; TNF and APOL-related leukocyte expressed ligand 1
Amount: 100 μg
Application Codes Clone: inhibit; block; in vivo
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody binds human BAFF protein and cross reacts with mouse and cynomolgus monkey BAFF protein. B-cell-activating factor (BAFF/CD257) is a cytokine belonging to the tumour-necrosis factor (TNF) family. This cytokine binds to TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. BAFF is a survival factor for B cells that controls B-cell maturation. It is also involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.
Application Notes: This antibody is capable of inhibiting the Blys signaling pathway by binding to Blys to block its binding to the receptor. The blocking activity of this antibody was reported to be better than Belimumab. In vitro, this antibody inhibited Blys-stimulated B cell proliferation and also inhibited Blys-stimulated mouse splenocyte proliferation. The original IgG1 version of this antibody binds BLyS with a very high binding affinity of Kd= 7.38E-10M. This antibody significantly inhibited human BLYS-induced activation and proliferation of splenic B cells in vivo (CN105061596).

Product Class:	Purified
Clone ID:	NMB04
Synonyms:	BLyS; TNFSF13B; TALL-1; TNFSF20; ZTNF4; Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; B-cell-activating factor; Dendritic cell-derived TNF-like molecule; TNF and APOL-related leukocyte expressed ligand 1
Amount:	100 μg
Application Codes Clone:	inhibit; block; in vivo
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody binds human BAFF protein and cross reacts with mouse and cynomolgus monkey BAFF protein. B-cell-activating factor (BAFF/CD257) is a cytokine belonging to the tumour-necrosis factor (TNF) family. This cytokine binds to TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. BAFF is a survival factor for B cells that controls B-cell maturation. It is also involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.
Application Notes:	This antibody is capable of inhibiting the Blys signaling pathway by binding to Blys to block its binding to the receptor. The blocking activity of this antibody was reported to be better than Belimumab. In vitro, this antibody inhibited Blys-stimulated B cell proliferation and also inhibited Blys-stimulated mouse splenocyte proliferation. The original IgG1 version of this antibody binds BLyS with a very high binding affinity of Kd= 7.38E-10M. This antibody significantly inhibited human BLYS-induced activation and proliferation of splenic B cells in vivo (CN105061596).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

Reviews