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Mfg Part Number

Ab03783-10.3

Vector Labs Ab03783-10.3 Anti-Benzopyrene [22F12], Human IgG1, Fc Silent™, kappa (100 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by using six B[a]P-protein conjugates B[a]P-6-C4-BSA, B[a]P-6-C4-KLH, B[a]P-7-C4-BSA, B[a]P-7-C4-KLH, B[a]P-10-C4-BSA and B[a]P-10-C4-KLH as immunogens for mouse immunizations.

$570.70

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Description

Product Class: Purified
Clone ID: 22F12
Heavy Chain Modification: Fc Silent™
Synonyms: B[a]P; PAHs; PAH; Benzo[a]pyrene; 3 4-Benzopyrene; polycyclic aromatic hydrocarbons; chrysene; indeno[1 2 3-cd]pyrene; benzo[b]fluoranthene
Amount: 100 μg
Application Codes Clone: ELISA
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: This antibody is specific for benzo[a]pyrene, which is an organic compound belonging to polycyclic aromatic hydrocarbon (PAH). Benzo[a]pyrene is one of the isomeric forms of benzopyrene. It comes from certain substances when they are not burned completely. It is found in car exhaust, smoke from wood fires, tobacco, oil and gas products, charred or grilled foods, and other sources. Traces of Benzopyrene are found in soil and water. It is also a causative agent for skin rashes, burning feeling, skin color changes, warts, bronchitis and even lung cancers.
Application Notes: This antibody was used in the development of a sensitive ELISA for the detection of benzopyrene in water. The average IC50 for B[a]P and corresponding detection limit at a signal : noise (S/N) ratio of 3 was 65 ng/L and 24 ng/L. This antibody also cross reacts with chrysene,indeno[1,2,3-cd]pyrene, and benzo[b]fluoranthene (PMID: 15965533).

Product Class:	Purified
Clone ID:	22F12
Heavy Chain Modification:	Fc Silent™
Synonyms:	B[a]P; PAHs; PAH; Benzo[a]pyrene; 3 4-Benzopyrene; polycyclic aromatic hydrocarbons; chrysene; indeno[1 2 3-cd]pyrene; benzo[b]fluoranthene
Amount:	100 μg
Application Codes Clone:	ELISA
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	This antibody is specific for benzo[a]pyrene, which is an organic compound belonging to polycyclic aromatic hydrocarbon (PAH). Benzo[a]pyrene is one of the isomeric forms of benzopyrene. It comes from certain substances when they are not burned completely. It is found in car exhaust, smoke from wood fires, tobacco, oil and gas products, charred or grilled foods, and other sources. Traces of Benzopyrene are found in soil and water. It is also a causative agent for skin rashes, burning feeling, skin color changes, warts, bronchitis and even lung cancers.
Application Notes:	This antibody was used in the development of a sensitive ELISA for the detection of benzopyrene in water. The average IC50 for B[a]P and corresponding detection limit at a signal : noise (S/N) ratio of 3 was 65 ng/L and 24 ng/L. This antibody also cross reacts with chrysene,indeno[1,2,3-cd]pyrene, and benzo[b]fluoranthene (PMID: 15965533).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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