Mfg Part Number
Ab03786-10.0
Vector Labs Ab03786-10.0 Anti-TGF beta1 [SL15S], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by panning a human phage antibody library against TGF beta1.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | SL15S |
| Synonyms: | TGFβ1; CAT-191; Kylie scFv; TGFB1, TGFB, Transforming growth factor beta-1, TGF-beta-1; Transforming growth factor beta-1 proprotein |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; Neutralizing |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for TGFβ1. It does not cross-react with TGFβ2 or TGFβ3. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis. The ability of the scFv fragment to recognise TGFβ1 and neutralise binding of TGFβ1 to A549 cells was measured in the radioreceptor assay. The scFv fragment was a highly potent, neutralising antibody for TGFβ1, with IC50 values in the range 0.03 to 0 1 nM. In particular, the scFv fragment could neutralise active, but not latent, TGFβ1 (US7151169B2). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |