Mfg Part Number
Ab03790-10.3
Vector Labs Ab03790-10.3 Anti-HCV E1 [5D2], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing 2 NOD/SCID mice with the monoclonal antibody TMβ1, PBMC from a human donor and E1s.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 5D2 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | HCV envelope protein 1; E1 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; Neutralizing; SPR |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for envelope protein 1 of Hepatitis C virus. The antibody recognizes an epitope in E1 represented by aa region 313-326. |
| Application Notes: | The specificity of the Fab format of the antibody was confirmed by ELISA analysis. Further, the antibody was able to neutralize genotype 2a, 1a and 4a of HCV. The affinity of the antibody was measured using peptide IGP 2254 (ITGHRMAWDMMMNWS). Association and dissociation of this peptide to the immobilized antibody was measured using SPR (Kd= 0.06 nM) (US20090104207). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |