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Mfg Part Number

Ab03797-10.0

Vector Labs Ab03797-10.0 Anti-HLA/EBNA1 [anti-HLA-A0201/EBNA1 antibody], Human IgG1, kappa (100 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by immunizing BALB/c mice with EBV nuclear antigen 1 (EBNA1) protein of Epstein Barr virus.

$570.70

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Description

Product Class: Purified
Clone ID: anti-HLA-A0201/EBNA1 antibody
Synonyms: Epstein-Barr nuclear antigen 1; EBV nuclear antigen 1
Amount: 100 μg
Application Codes Clone: SPR; IHC; FC
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: The antibody targets Epstein-Barr virus (EBV) associated tumor cells by binding to HLA/EBNA1 peptide complexes. The antibody recognizes EBNA1 epitope presented on HLA-A0201, HLA-A203, HLA-A0206 and HLA-A0207. Epstein-Barr Virus (EBV) is a ubiquitous human herpesvirus, which is found as a predominantly asymptomatic infection in all human communities. EBV has been linked to numerous human tumours of diverse tissue origin.
Application Notes: The antibody is specific for EBV-EBNA-1, as detected by FC. The binding affinity of the original format of the antibody to HLA-A0201/EBNA-1 was measured by surface plasmon resonance (Kd= 6.02nM). This antibody was used for detection of HLA-A0201/EBNA1 complexes expressed on CCRF-SB and RPMI6666 tumour cells by flow cytometry. The antibody was used for immunological staining of EBV infected-HLA-A0201 positive nasopharyngeal carcinoma (NPC) biopsy. This biopsy was observed to stain positive for HLA-A0201/EBNA1 complexes (WO2015199617A1).

Product Class:	Purified
Clone ID:	anti-HLA-A0201/EBNA1 antibody
Synonyms:	Epstein-Barr nuclear antigen 1; EBV nuclear antigen 1
Amount:	100 μg
Application Codes Clone:	SPR; IHC; FC
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:	The antibody targets Epstein-Barr virus (EBV) associated tumor cells by binding to HLA/EBNA1 peptide complexes. The antibody recognizes EBNA1 epitope presented on HLA-A0201, HLA-A203, HLA-A0206 and HLA-A0207. Epstein-Barr Virus (EBV) is a ubiquitous human herpesvirus, which is found as a predominantly asymptomatic infection in all human communities. EBV has been linked to numerous human tumours of diverse tissue origin.
Application Notes:	The antibody is specific for EBV-EBNA-1, as detected by FC. The binding affinity of the original format of the antibody to HLA-A0201/EBNA-1 was measured by surface plasmon resonance (Kd= 6.02nM). This antibody was used for detection of HLA-A0201/EBNA1 complexes expressed on CCRF-SB and RPMI6666 tumour cells by flow cytometry. The antibody was used for immunological staining of EBV infected-HLA-A0201 positive nasopharyngeal carcinoma (NPC) biopsy. This biopsy was observed to stain positive for HLA-A0201/EBNA1 complexes (WO2015199617A1).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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