Mfg Part Number
Ab03798-10.0
Vector Labs Ab03798-10.0 Anti-PVRIG [334MXX], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing mice with human PVRIG linked to a human IgG Fc region.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 334MXX |
| Synonyms: | Poliovirus receptor-related immunoglobulin domain-containing protein; Transmembrane protein PVRIG; CD112 receptor (CD112R) |
| Amount: | 100 μg |
| Application Codes Clone: | FACS |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody specifically binds to human PVRIG. |
| Application Notes: | The original version and the humanized version antibody were able to inhibit PVRIG activity and signaling. The binding of the original format or the humanized version of the antibody to PVRIG decreased PVRL2 activity, as shown by FACS analysis on HEK-293T cells transfected with hPVRIG (WO2018017864A3). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |