Mfg Part Number
Ab03800-10.3
Vector Labs Ab03800-10.3 Anti-FZD7 [Fab-1791], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
Vector Labs Ab03800-10.3 Anti-FZD7 [Fab-1791], Human IgG1, Fc Silent™, kappa (100 μg)
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | Fab-1791 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | human frizzled receptor; Frizzled-7; Fz-7; hFz7; FzE3 |
| Amount: | 100 μg |
| Application Codes Clone: | WB; in vitro; FC; IHC; blocking |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for FZD7. The antibody recognises human FZD7, but not with mouse FZD7. |
| Application Notes: | The antibody detected the recombinant human FZD7 by western blot analysis. The antibody reduced FZD7 signaling in breast cancer cell line MDA- B-231 about 3-fold. This antibody was used for detection of FZD7 expressed on OVCAR4 cells by flow cytometry. The antibody could block migration of a breast cancer cell line and ovarian cancer cell line OVCAR4. This antibody was used for immunohistochemistry on ovarian carcinoma and renal cell carcinoma samples (WO2016205566A1). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |