Mfg Part Number
Ab03811-30.11
Vector Labs Ab03811-30.11 Anti-MerTK [Ab2000], scFv fragment (His), ScFv, (100 μg)
Quick Overview
The original antibody was generated by phage display method. A phage display library was screened against the extracellular domain of human and/or mouse MerTK.
$692.90
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| Product Class: | Purified |
|---|---|
| Clone ID: | Ab2000 |
| Heavy Chain Modification: | ScFv |
| Synonyms: | Tyrosine-protein kinase Mer; EC:2.7.10.1; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; Inhibition |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | The antibody specifically binds to human MerTK. |
| Application Notes: | The specificity of the IgG1 format of the antibody was confirmed by ELISA analysis. The antibody bound to cellularly expressed full length human MerTK in a dose responsive manner, with EC50 values in the picomolar to nanomolar range, as determined by FACS. The antibody inhibited Gas6 binding to hMerTK in a dose responsive manner, with an IC50 of 1 nM (WO2019084307A1). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |