Mfg Part Number
Ab03827-23.0
Vector Labs Ab03827-23.0 Anti-DLL4 [mh2F], Rabbit IgG, lambda (100 μg)
Quick Overview
Vector Labs Ab03827-23.0 Anti-DLL4 [mh2F], Rabbit IgG, lambda (100 μg)
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | mh2F |
| Synonyms: | Delta-like protein 4; Drosophila Delta homolog 4 (Delta4) |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; SPR; inhibition; in vivo |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for human and mouse DLL4. |
| Application Notes: | The binding affinity of the antibody to DLL4 was measured by surface plasmon resonance (Kd= 5 nM). The specificity of the original format of the antibody for human and mouse DLL4 was confirmed by ELISA analysis. The antibody inhibited the binding between DLL4 and the Notch receptor, thereby inhibiting Notch signaling. The antibody was shown to reduce the size of the tumor in mice transplanted with human lung cancer cells A549 cells (KR1020140085790A). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |