Mfg Part Number
Ab03828-10.3
Vector Labs Ab03828-10.3 Anti-MERS-CoV Spike protein [2E6], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing Bab/c mice with high-purity MERS-RBD protein.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 2E6 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Spike gylcoprotein; S glycoprotein; E2; Peplomer protein;Spike protein S1; The Middle East Respiratory Syndrome Cononavirus |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; NTRL; FC; SPR |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for the Spike protein of MERS Coronavirus. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody inhibited the binding of MERS virus S protein to cell surface receptor CD26 by flow cytometry. The antibody could neutralize the virus (pseudovirus and live virus) as shown by virus neutralization test. The binding affinity of the antibody to MERS RBD protein was measured by surface plasmon resonance (Kd= 9 nM) (CN104447986A). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |