Mfg Part Number
Ab03830-1.1
Vector Labs Ab03830-1.1 Anti-MUC1-C/ECD [6A6], Mouse IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing C57Bl/6 mice with a protein containing ECD of MUC1-C fused to the Fc portion of mouse immunoglobulin (MUC1-C/ECD-mFc).
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 6A6 |
| Synonyms: | MUC1-C/extracellular domain; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3 (CA 15-3); Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6 (KL-6); PEMT; Peanut-reactive urinary mucin (PUM); Polymorphic epithelial mucin (PEM); Tumor-associated epithelial membrane antigen (EMA); Tumor-associated mucin |
| Amount: | 100 μg |
| Application Codes Clone: | FC; ELISA; WB; therapeutic |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | The antibody is specific for MUC1-C/ECD. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis. This antibody was used for detection of MUC1-C/ECD expressed on ZR-75-1 breast carcinoma or H-1975 NSCLC cell lines by flow cytometry. The antibody detected the recombinant chIL-2 by western blot analysis (US10059775B2). The scFv version of this antibody was successfully used to deliver gemcitabine to MUC1-positive pancreatic cancer cells, enhancing chemosensitivity and inducing immunogenic cell death in both in vitro and in vivo models of pancreatic ductal adenocarcinoma (PDAC) (Guo et al., 2024; DOI: 10.1002/smm2.1279). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |