Mfg Part Number
Ab03845-23.0
Vector Labs Ab03845-23.0 Anti-gp120 protein (CD4-binding domain) [559/64-D], Rabbit IgG, kappa (100 μg)
Quick Overview
The antibody was generated by fusing Ab-producing cells pooled from two separate patients.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 559/64-D |
| Synonyms: | CD4-bd; Surface protein gp120; Glycoprotein 120; gp120 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; Neutralization; blocking |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 25965315 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody recognises a conformational epitopes of the gp120 envelope protein of HIV-1. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody was able to block the interaction between recombinant CD4 (rCD4) and rgp120. It was also able to achieve 50% neutralization of HTLV-IIIB and MN strains of HIV-1 in a concentration range of 0.5-12.8 micrograms/mL. The binding affinity of the antibody for gp120 in solution was measured, dissociation constants (Kd) equal to 40 nM. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |