Mfg Part Number
Ab03853-1.1
Vector Labs Ab03853-1.1 Anti-Ghrelin [5A1], Mouse IgG1, kappa (100 μg)
Quick Overview
Vector Labs Ab03853-1.1 Anti-Ghrelin [5A1], Mouse IgG1, kappa (100 μg)
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 5A1 |
| Synonyms: | GHRL; MTLRP; Appetite-regulating hormone; Growth hormone secretagogue; Growth hormone-releasing peptide; Motilin-related peptide; Protein M46 |
| Amount: | 100 μg |
| Application Codes Clone: | SPR; in vivo |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | Fab |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted mouse antibody was made using the variable domain sequences of the original Mouse Fab format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody recognises ghrelin. Ghrelin is a hormone produced by enteroendocrine cells of the gastrointestinal tract, especially the stomach and is often called a "hunger hormone" because it increases the drive to eat. |
| Application Notes: | The kinetic constant of the humanized, affinity matured Fab version of the antibody was measured by KinExA (Kd= 1 pM). The binding affinity of the Fab fragment to Ghrelin was measured by surface plasmon resonance (Kd= 2 pM). Rats were injected with human ghrelin and their food consumption was measured. Results showed that if the humanized Fab version of the antibody was administrated, their food consumption was effectively reduced (US7479271). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |