Mfg Part Number
Ab03857-10.0
Vector Labs Ab03857-10.0 Anti-CD28 [PV1], Human IgG1, kappa (100 μg)
Quick Overview
The antibody was generated using C57BL/6N mouse T cell lymphoma EL4 cell line as antigen.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | PV1 |
| Synonyms: | T-cell-specific surface glycoprotein CD28; CD28 receptor |
| Amount: | 100 μg |
| Application Codes Clone: | FC; IP |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody binds specifically to murine CD28. |
| Application Notes: | CD28-positive murine T cell line EL4 cells were stained with the antibody and analyzed by flow cytometry (US20040116675A1). Protein lysates from J558 were immunoprecipitated with the antibody (Rozanski et al., 2015; PMID: 25833397). Anti-CD28-PV1-IgG3 is the hamster-mouse chimeric version of the antibody. The antibody enabled long-term survival of heart allografts in rats by reducing the activation of alloantigen-mediated key signaling events in T cells (Jang et al. 2008; PMID: 18408588). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |