Mfg Part Number
Ab03858-23.0
Vector Labs Ab03858-23.0 Anti-TIGIT [1F4], Rabbit IgG, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing hamsters with murine TIGIT-Fc fusion protein.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 1F4 |
| Synonyms: | T-Cell-Ig and ITIM domain; T-cell immunoreceptor with Ig and ITIM domains; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain-containing protein 3 |
| Amount: | 100 μg |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for human TIGIT. TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |