Mfg Part Number
Ab03867-10.0
Vector Labs Ab03867-10.0 Anti-NT-proBNP [1-10], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by introducing site directed mutations in CDRs of the parental mouse antibody.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 1-10 |
| Synonyms: | BNP; NT-pro-BNP; NT-proBNP(1-76); hBNP; NPPB; NT-proB-type natriuretic peptide; preproBNP; B-type natriuretic peptide; Natriuretic peptides B; Brain natriuretic factor prohormone; Brain natriuretic peptide; Gamma-brain natriuretic peptide; Iso-ANP |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds NT-proB-type natriuretic peptide (NT-proBNP), a 76 amino acid cleaved N-terminal (NT)-pro hormone BNP (NT-proBNP), which is a non-active prohormone that is released from the protein proBNP. BNP is a naturally secreted cardiac regulatory hormone that influences blood pressure and vascular water retention in human physiology. The plasma BNP and NT-proBNP concentration are clinically recognized biomarkers for various cardiovascular diseases. |
| Application Notes: | The original mouse IgG antibody binds human NT-proBNP with a binding affinity of Kd= 1.6 X 10^(-10) M. This antibody can be used for the detection of NT-proBNP in a sample using ELISA (CN113004405). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |