Mfg Part Number
Ab03869-10.3
Vector Labs Ab03869-10.3 Anti-proBNP [106.3], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original mouse antibody was generated by immunizing mice with human BNP peptide 5-13 (VQGSGAFGR) conjugated with BSA.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 106.3 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | BNP; hBNP; NPPB; preproBNP; B-type natriuretic peptide; Natriuretic peptides B; Brain natriuretic factor prohormone; Brain natriuretic peptide; Gamma-brain natriuretic peptide; Iso-ANP; HB-12044 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds B-type natriuretic peptide (BNP) 5‐13 (VQGSGAFGR). BNP is a naturally secreted cardiac regulatory hormone that influences blood pressure and vascular water retention in human physiology. The plasma BNP concentration is a clinically recognized biomarker for various cardiovascular diseases. |
| Application Notes: | This antibody can be used for the detection of human BNP using ELISA (PMID: 18606632). This antibody when crosslinked to POROS XL ID resin can also be used in the immunoprecipitation of BNP from plasma samples of patients with chronic heart failure (PMID: 16750161). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |