Mfg Part Number
Ab03870-2.3
Vector Labs Ab03870-2.3 Anti-HbA1c [1G8], Mouse IgG2a, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with synthetic N-terminal glycopeptide (VHLTPEC) and KLH conjugate.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 1G8 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | GHb; A1C; HBB; hemoglobin A1c; glycosylated hemoglobin HbA1c; glycosylated hemoglobin; glycohemoglobin; glycated hemoglobin; haemoglobin; haemoglobin A1c; Hemoglobin subunit beta; Beta-globin; Hemoglobin beta chain |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody binds human hemoglobin glycated at the N-terminal valine of the hemoglobin β chain and does not cross react with non-glycated hemoglobin. Glycated hemoglobin is formed by the conjugation of a hexose sugar to the beta-chain of hemoglobin. Glycosylated hemoglobin A1c (HbA1c) levels are used as an indicator of average plasma glucose concentration in diabetic patients. Levels of more than 48 mmol/mol (6.5%) are used as a criterion for the diagnosis of diabetes. Higher levels of HbA1c are also associated with cardiovascular disease. |
| Application Notes: | This antibody is recommended for detection of HbA1c levels in plasma and blood samples. The binding reactivity of this antibody towards HbA1c and non-glycated hemoglobin was done using indirect ELISA. The binding reactivity of this antibody to HbA1c was compared to commercially available anti-HbA1c antibody BM300-F7C2 and it was reported that this antibody showed better specificity for HbA1c (CN110724671). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |