Mfg Part Number
Ab03889-1.1
Vector Labs Ab03889-1.1 Anti-HBV pre-S2 protein [1F6], Mouse IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing mice with purified HBsAg containing pre-S1 and pre-S2 proteins.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | 1F6 |
| Synonyms: | PreS2; Large envelope protein; L glycoprotein; L-HBsAg; Large S protein; Large surface protein; Major surface antigen |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody binds an epitope 'DPRVRGLYF' (amino acids 131-141) of the pre-S2 region of the hepatitis B virus. Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus (HBV). It can cause chronic infection and puts people at high risk of death from cirrhosis and liver cancer. |
| Application Notes: | The binding reactivity and affinity of this antibody towards HBV pre-S2 protein was determined using ELISA. The original mouse IgG1 version of this antibody was reported to bind pre-S2 protein of HBV with a binding affinity of Kd= 1.2 nM (PMID: 10509818). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |