Mfg Part Number
Ab03902-3.3
Vector Labs Ab03902-3.3 Anti-CD155 [scFv1], Mouse IgG2b, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was isolated from an scFv phage display library generated by immunizing two BALB/c mice intradermally with paraformaldehyde fixed HT1080 cells (human fibrosarcoma cell line).
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| Product Class: | Purified |
|---|---|
| Clone ID: | scFv1 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | PVR; PVS; NECL-5; Poliovirus receptor; Nectin-like protein 5 |
| Amount: | 100 μg |
| Application Codes Clone: | FC; IP |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds human CD155 also called the poliovirus receptor (PVR). This protein mediates NK cell adhesion and triggers NK cell function. It also binds two NK cell receptors CD96 and CD226. CD155 is gaining more interest as a therapeutic target in the field of tumor immunology due to its prominent endogenous and immune functions. |
| Application Notes: | The ability of this antibody to bind HT1080,PC3, KHOS and chang liver cells was determined using flow cytometry. This antibody was also capable of immunoprecipitating a 70 kDa protein from HT1080 cell extract (US20090215175). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |