Mfg Part Number
Ab03920-1.1
Vector Labs Ab03920-1.1 Anti-M protein, serotype 5 [49.8.9], Mouse IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c BYJ mice with streptococcal M type 5 membranes followed by a second, boosting dose of M type 5 streptococcal membranes.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 49.8.9 |
| Synonyms: | Myosin; Streptococcal M-protein; Keratin; DNA; Vimentin; Troponin; Ganglioside; Glycophorin M,N |
| Amount: | 100 μg |
| Application Codes Clone: | WB; HA; PRNT; ELISA |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 11282394 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody reacts with α-helical molecules and the carbohydrate N-acetyl-b-D-glucosamine (GlcNac). Specifically, it binds streptococcal M-protein (type 5), human myosin, keratin, DNA, vimentin, troponin, ganglioside, and glycophorin M,N. |
| Application Notes: | This antibody reacts with human heart cells and whole streptococci (group A, M type 5), as shown in an ELISA, and with human heart cells, human sarcolemma (weak response), and group A streptococcal membranes (weak response), as shown in a WB (Cunnigham et al., 1984; PMID: 6384047). This antibody labels the cytoplasm of epidermal cells and epidermal appendages in normal and psoriatic skin, as shown by immunofluorescent staining (Swerlick et al., 1986; PMID: 3525693). This antibody binds CV (B3), as shown in an ELISA; neutralizes PV-1 and CV (B3), as shown in a plaque-reduction neutralization assay; and is slightly cytotoxic to rat fibroblasts, as shown in a cytotoxicity assay (Cunningham et al., 1992; PMID: 1311095). This antibody reacts with retinal S-antigen (S-Ag), as shown in an ELISA (Lerner et al., 1995; PMID: 8722579). This antibody binds myosin at a medium relative avidity, as determined in a competitive ELISA. Reactivity with glycophorin M and N was determined by hemagglutination assay (Mertens et al., 2000; PMID: 11282394). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |