Mfg Part Number
Ab03939-10.0
Vector Labs Ab03939-10.0 Anti-Apolipoprotein B-100 [MabB9], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing female BALB/c mice intraperitoneally with 20ug of human apo B-100 and dead Salmonella microbes.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | MabB9 |
| Synonyms: | APOB; Apolipoprotein B-100; Apo B-100 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds human apolipoprotein B (APOB). Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. It is involved in the metabolism of lipids and is the main protein constituent of lipoproteins such as very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL, the “bad cholesterol”). |
| Application Notes: | The binding characterization of this antibody towards human APO-B was done using ELISA and immunoblotting. This antibody was also used in a serum assay to determine the quantity of apo-B in a sample using competitive ELISA. This antibody was shown to react with isolated human Apo-B as well as low density lipids but not with high density lipids and lipoprotein-deficient serum (Yoon et al., 1993). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |