Mfg Part Number
Ab03943-10.3
Vector Labs Ab03943-10.3 Anti-Ferritin [F11 (HSF102)], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing female Balb/c mice with ferritin extracted from human spleen cells.
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| Product Class: | Purified |
|---|---|
| Clone ID: | F11 (HSF102) |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | FTMT; FTL; FTH1; Ferritin mitochondrial; B8 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 9891990 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds human ferritin. This protein catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Ferritin is important for iron homeostasis. |
| Application Notes: | The binding characterization of this antibody towards human spleen ferritin was done using ELISA. This antibody was also reported to show binding affinity for protein A. Binding of this antibody to ferritin causes antigen-induced conformational changes in the antibody and reduces its affinity for protein A (PMID: 9776583). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |