Mfg Part Number
Ab03953-10.3
Vector Labs Ab03953-10.3 Anti-LAG3 [AbAbLAG3], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing transgenic HuMab or KM mice with recombinant human LAG-3 protein.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | AbAbLAG3 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Lymphocyte-activation gene-3; Lymphocyte activation gene 3 protein; CD223; LAG-3; CGMCNO 20774 |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; inhibit; in vitro |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | The antibody is specific for LAG3. Lymphocyte activation gene 3 protein is an inhibitory receptor on antigen activated T-cells. It delivers inhibitory signals upon binding to ligands, such as FGL1. |
| Application Notes: | The binding characterization of this antibody to human LAG3-Fc fusion protein was done using ELISA. The original human IgG antibody was reported to bind human LAG-3 in the sub picomolar range. This antibody was effective in inhibiting the binding of LAG3 to MHC class II molecules in an in vitro binding assay. In the antigen-specific T cell response assay, this antibody can stimulate the production of IL-2 (CN109748963). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |