Mfg Part Number
Ab03954-23.0
Vector Labs Ab03954-23.0 Anti-D-Dimer [MA-15C5], Rabbit IgG, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with purified fragment D-dimer from cross linked human fibrin.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | MA-15C5 |
| Synonyms: | XDP; Fragment D-dimer; Fibrin degradation fragment; Fibrin degradation product; Fibrin |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; imaging |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 1885569 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is directed against a neoantigenic determinant expressed on the human fragment D-dimer. D-dimer is a protein fragment (small piece) that's made when a blood clot dissolves in your body. At D-dimer test is done to determine if a person has any blood clotting disorder. |
| Application Notes: | This antibody has a 1000 fold higher affinity for binding human fragment D-dimer than for human fibrinogen. It could effectively bind D-dimer from human plasma clots and can be used for thrombus imaging in an animal model in vivo (PMID: 2749602). This antibody has been used in an ELISA assay for the quantification of fragment-D dimer in plasma (PMID: 3127914). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |