Mfg Part Number
Ab03964-10.3
Vector Labs Ab03964-10.3 Anti-HLA class I [F17B1], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing male MRL/lpr mice with an an emulsion containing complete adjuvant H37Ra and purified sHLA-A-flag protein.
$570.70
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | F17B1 |
| Heavy Chain Modification: | Fc Silent™ |
| Amount: | 100 μg |
| Application Codes Clone: | FACS; FC; in vivo |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for HLA class I. The antibody binds to the following subclasses: A2, A3, A11, A23, A24, A25, A26, A29, A30, A31, A32, A33, A34, A68. |
| Application Notes: | The original antibody showed strong cell death-inducing activity by FACS analysis. The antibody was used for detection of beads coated HLA class I antigen by flow cytometry. The human chimeric and the humanized version of the antibody was constructed. The human chimeric antibody was administered into a mouse model for human myeloma. The result showed that the antibody can significantly prolong the survival period of the mouse model for human myeloma. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |