Vector Labs Ab03988-1.1 Anti-CD3 [CA17.2A12], Mouse IgG1, kappa (100 μg) Centrifuge Bundle Savings at Sycamore Life Sciences

Description

Product Class: Purified
Clone ID: CA17.2A12
Synonyms: TCR/CD3; TCR-2; TCR-αβ; TCR-ab; TCR-alphabeta
Amount: 100 μg
Application Codes Clone: FC; IHC; Activation
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Specificity Statement: This bispecific antibody is specific for canine TCR-2 (TCR-αβ) and CD3.
Application Notes: This antibody was used as an immune phenotype marker in flow cytometric (FC) analyses of peripheral blood lymphocytes (PBL) in dogs to identify T cells (specifically, CD3) (Helfand et al., 1995; PMID: 7605993). Later, it was used for immunophenotyping by FC to identify T-cell antigen CD3 in dogs with lymphocytosis (McDonough et al., 2000; PMID: 11105953) and as a T-lymphocyte marker in blood and bone marrow samples from dogs with hematologic disorders (Weiss, 2001; PMID: 11817066). It was also used in FC analysis of various cell populations, including peripheral blood and lymph nodes, to identify CD3⁺ T cells in a study on apoptosis (Pappalardoa et al., 2001; PMID: 11730925). Most recently, it was used to stain leukocytes for analysis by FC as part of a Canine leukocyte suppression assay (LSA) (Amorim et al., 2020; PMID: 32698861), to identify CD3 in fine-needle aspirates of canine nodal lymphomas (Rigillo et al., 2021; PMID: 33759339), and to stain CD3 on canine peripheral blood mononuclear cells (PBMC) (Ruiz et al., 2022; PMID: 36217551). Additionally, this antibody was used to detect CD3 in immunohistology studies (specifically IHC) of the liver and spleen in dogs treated with rcGM-CSF (Nash et al., 1995; PMID: 7655007). This antibody was fixed to magnetic beads and used for the activation of canine peripheral blood lymphocytes (Szopa et al., 2021; PMID: 33679741). If you are interested in canine bispecific T-cell engagers, please contact us.

Product Class:	Purified
Clone ID:	CA17.2A12
Synonyms:	TCR/CD3; TCR-2; TCR-αβ; TCR-ab; TCR-alphabeta
Amount:	100 μg
Application Codes Clone:	FC; IHC; Activation
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Specificity Statement:	This bispecific antibody is specific for canine TCR-2 (TCR-αβ) and CD3.
Application Notes:	This antibody was used as an immune phenotype marker in flow cytometric (FC) analyses of peripheral blood lymphocytes (PBL) in dogs to identify T cells (specifically, CD3) (Helfand et al., 1995; PMID: 7605993). Later, it was used for immunophenotyping by FC to identify T-cell antigen CD3 in dogs with lymphocytosis (McDonough et al., 2000; PMID: 11105953) and as a T-lymphocyte marker in blood and bone marrow samples from dogs with hematologic disorders (Weiss, 2001; PMID: 11817066). It was also used in FC analysis of various cell populations, including peripheral blood and lymph nodes, to identify CD3⁺ T cells in a study on apoptosis (Pappalardoa et al., 2001; PMID: 11730925). Most recently, it was used to stain leukocytes for analysis by FC as part of a Canine leukocyte suppression assay (LSA) (Amorim et al., 2020; PMID: 32698861), to identify CD3 in fine-needle aspirates of canine nodal lymphomas (Rigillo et al., 2021; PMID: 33759339), and to stain CD3 on canine peripheral blood mononuclear cells (PBMC) (Ruiz et al., 2022; PMID: 36217551). Additionally, this antibody was used to detect CD3 in immunohistology studies (specifically IHC) of the liver and spleen in dogs treated with rcGM-CSF (Nash et al., 1995; PMID: 7655007). This antibody was fixed to magnetic beads and used for the activation of canine peripheral blood lymphocytes (Szopa et al., 2021; PMID: 33679741). If you are interested in canine bispecific T-cell engagers, please contact us.

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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